HYPOXIA-RESPONSIVE NANOREACTORS BASED ON SELF-ENHANCED PHOTODYNAMIC SENSITIZATION AND TRIGGERED FERROPTOSIS FOR CANCER SYNERGISTIC THERAPY

Hypoxia-responsive nanoreactors based on self-enhanced photodynamic sensitization and triggered ferroptosis for cancer synergistic therapy

Abstract Background Photodynamic therapy (PDT), a typical reactive oxygen species (ROS)-dependent treatment with high controllability, has emerged as an alternative cancer therapy modality but its therapeutic efficacy is still unsatisfactory due to the limited light penetration and constant oxygen consumption.With the development of another ROS-dep

read more

NO, ROS, RAS, and PVAT: More Than a Soup of Letters

Perivascular adipose tissue (PVAT) has recently entered in the realm of cardiovascular diseases as a putative target for intervention.Notwithstanding its relevance, there is still a long way Suspension Stabilizer Bar Link Kit before the role of PVAT in physiology and pathology is fully understood.The general idea that PVAT anti-contractile effect i

read more

Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm

The study included 15patients with coronary heart disease (CHD), post-infarction cardiosclerosis, and chronic left ventricular (LV) aneurysm.All patients underwent interventional myocardial revascularization and Dor aneurysmectomy.Myocardial scintigraphy with 99mTc-MYOVIEW was performed at baseline (during nitroglycerine test and at rest), and 3-4

read more